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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
St6gal1tm1Jxm
targeted mutation 1, Jamey Marth
MGI:2387745
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
St6gal1tm1Jxm/St6gal1tm1Jxm involves: 129S1/Sv * 129X1/SvJ MGI:2655846


Genotype
MGI:2655846
hm1
Allelic
Composition
St6gal1tm1Jxm/St6gal1tm1Jxm
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
St6gal1tm1Jxm mutation (0 available); any St6gal1 mutation (57 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• intraperitoneal thioglycollate elicitation recruits double the number of leukocyte cells compared to controls one day after elicitation
• T2 follicular and marginal zone precursors are reduced by 65% and 87%, respectively
• stimulating the release of neutrophils from the bone marrow by G-CSF administration leads to twice as many neutrophils in circulation as controls
• marginal zone B cell numbers are reduced by about half
• immature dendritic cells (iDC) are unable to inhibit B cell activation from a distance as wild-type iDC are

digestive/alimentary system
• intraperitoneal thioglycollate elicitation recruits double the number of leukocyte cells compared to controls one day after elicitation

hematopoietic system
• T2 follicular and marginal zone precursors are reduced by 65% and 87%, respectively
• stimulating the release of neutrophils from the bone marrow by G-CSF administration leads to twice as many neutrophils in circulation as controls
• marginal zone B cell numbers are reduced by about half





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory