mortality/aging
• at implantation stage
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Allele Symbol Allele Name Allele ID |
Pafah1b1tm1Or targeted mutation 1, Orly Reiner MGI:2387783 |
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Summary |
2 genotypes
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|
|
♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• at implantation stage
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|
|
♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• abnormal organization of radial glia
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• abnormal emergence of cortical plate in caudal and medial regions of dorsal telencephalon
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• delayed formation of the cortical plate
• delayed neuronal migration in the cortex
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• abnormal organization of radial glia
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
lissencephaly | DOID:0050453 |
OMIM:PS607432 |
J:69631 | |
Miller-Dieker lissencephaly syndrome | DOID:0060469 |
OMIM:247200 |
J:69631 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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