All Phenotypes Odc1<tm1Jlc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Odc1^tm1Jlc
targeted mutation 1, John L Cleveland
MGI:2387837

Summary

2 genotypes

Allelic Composition	Odc1^tm1Jlc/Odc1^tm1Jlc
Genetic Background	involves: 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Odc1^tm1Jlc mutation (0 available); any Odc1 mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• embryos develop normally to the blastocyst stage and implant but die shortly thereafter, before the onset of gastrulation

embryo

abnormal inner cell mass apoptosis ( J:71462 )

• E3.5 embryos show an increase in TUNEL-positive cells in the inner cell mass

cellular

abnormal inner cell mass apoptosis ( J:71462 )

• E3.5 embryos show an increase in TUNEL-positive cells in the inner cell mass

Allelic Composition	Odc1^tm1Jlc/Odc1⁺
Genetic Background	involves: 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Odc1^tm1Jlc mutation (0 available); any Odc1 mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:71462 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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