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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Vav1tm1Bbd
targeted mutation 1, Mariano Barbacid
MGI:2387839
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Vav1tm1Bbd/Vav1tm1Bbd involves: 129S2/SvPas * C57BL/6J MGI:3834172
ht2
 		Vav1tm1Bbd/Vav1+ involves: 129S2/SvPas * C57BL/6J MGI:3834171


Genotype
MGI:3834172
hm1
Allelic
Composition		 Vav1tm1Bbd/Vav1tm1Bbd
Genetic
Background		 involves: 129S2/SvPas * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vav1tm1Bbd mutation (0 available); any Vav1 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

embryo
failure of blastocyst to hatch from the zona pellucida ( J:22517 )
• cultured embryos fail to hatch from the zona pellucida




Genotype
MGI:3834171
ht2
Allelic
Composition		 Vav1tm1Bbd/Vav1+
Genetic
Background		 involves: 129S2/SvPas * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vav1tm1Bbd mutation (0 available); any Vav1 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
transmission ratio distortion ( J:22517 )
• slight distortion in favor of heterozygous mice over wild type mice at birth




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory