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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Omptm1Flm
targeted mutation 1, Frank L Margolis
MGI:2387862
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Omptm1Flm/Omptm1Flm involves: 129S1/Sv MGI:3622787


Genotype
MGI:3622787
hm1
Allelic
Composition
Omptm1Flm/Omptm1Flm
Genetic
Background
involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Omptm1Flm mutation (1 available); any Omp mutation (27 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
taste/olfaction
• electoolfactogram response magnitudes from olfactory epithelium of null mice in response to isoamyl acetate are 25% lower than in wild-type; responses to all other chemical odors tested are 20-40% smaller than in wild-type

homeostasis/metabolism
• tyrosine hydroxylase activity in null olfactory bulbs are 65% lower than wild-type

nervous system
• olfactory bulb weight is 15% less in mutants than in wild-type at 1 to 2 months after birth





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory