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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(SOD1)3Cje
transgene insertion 3, Charles J Epstein
MGI:2387864
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(SOD1)3Cje/0 C57BL/6-Tg(SOD1)3Cje/J MGI:3693620
tg2
 		Tg(SOD1)3Cje/0 involves: BALB/c * C57BL/6J * DBA/2 MGI:3783736


Genotype
MGI:3693620
tg1
Allelic
Composition		 Tg(SOD1)3Cje/0
Genetic
Background		 C57BL/6-Tg(SOD1)3Cje/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(SOD1)3Cje mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
decreased threshold for auditory brainstem response ( J:102419 )
• over-expression of SOD1 does not protect against hearing loss except at 24 months of age, when hemizygous transgenic mice display slightly reduced ABR thresholds relative to age-matched C57BL/6 control mice




Genotype
MGI:3783736
tg2
Allelic
Composition		 Tg(SOD1)3Cje/0
Genetic
Background		 involves: BALB/c * C57BL/6J * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(SOD1)3Cje mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
myocardium necrosis ( J:89952 )
• extent of myocardial necrosis following ischemia and reperfusion is similar to that observed in wild-type

muscle
myocardium necrosis ( J:89952 )
• extent of myocardial necrosis following ischemia and reperfusion is similar to that observed in wild-type




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory