Phenotypes associated with this allele

• Allele Symbol: Mcf2^tm1Ehi
• Allele Name: targeted mutation 1, Emilio Hirsch
• Allele ID: MGI:2388053
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mcf2^tm1Ehi/Mcf2^tm1Ehi	involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:3784072

Genotype
MGI:3784072

hm1

• Allelic Composition: Mcf2^tm1Ehi/Mcf2^tm1Ehi
• Genetic Background: involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:78933 )

♀N • morphologically, brains appear normal

♀N • distributions of neuronal populations in the cortex are normal

abnormal dendrite morphology ( J:78933 )

♀ • at P7, basal dendrites in corticocollicular and callosally projecting neurons are shorter than in wild-type cells

♀ • apical dendrites tend to be shorter in mutant brains

behavior/neurological

behavior/neurological phenotype ( J:78933 )

♀N • mice show no alterations in behavior with posture, coordination, sensorial discrimination, feeding and socialization being similar to controls

reproductive system

reproductive system phenotype ( J:78933 )

♀N • males and females demonstrate normal reproductive abilities

♀N • histologically, ovaries are normal

♀N • testis morphology and sperm production are normal in males