immune system
• B cells fail to induce class switch recombination in response to Tnfsf13 (APRIL) ligand
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• B cells fail to produce IgA immunoglobulins in response to Tnfsf13 or Tnfsf13b ligands
• synthesize of IgA in response to LPS and TGF-beta is normal
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• B cells fail to produce IgE immunoglobulins in response to Tnfsf13 ligand
• synthesize of IgE in response to LPS and IL-4 is normal
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• B cells fail to produce IgG1 immunoglobulins in response to Tnfsf13 ligand
• synthesize of IgG1 in response to LPS and IL-4 is normal
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hematopoietic system
• B cells fail to induce class switch recombination in response to Tnfsf13 (APRIL) ligand
|
• B cells fail to produce IgA immunoglobulins in response to Tnfsf13 or Tnfsf13b ligands
• synthesize of IgA in response to LPS and TGF-beta is normal
|
• B cells fail to produce IgE immunoglobulins in response to Tnfsf13 ligand
• synthesize of IgE in response to LPS and IL-4 is normal
|
• B cells fail to produce IgG1 immunoglobulins in response to Tnfsf13 ligand
• synthesize of IgG1 in response to LPS and IL-4 is normal
|