Phenotypes associated with this allele

• Allele Symbol: Dstn^corn1-2J
• Allele Name: corneal disease 1, 2 Jackson
• Allele ID: MGI:2388156
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dstn^corn1-2J/Dstn^corn1-2J	C57BL/6JSmn-Dstn^corn1-2J/J	MGI:2660805
ht2	Dstn^corn1/Dstn^corn1-2J	involves: A/WySn * brachy stock * C57BL/6JSmn	MGI:3817224

Genotype
MGI:2660805

hm1

• Allelic Composition: Dstn^corn1-2J/Dstn^corn1-2J
• Genetic Background: C57BL/6JSmn-Dstn^corn1-2J/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

vision/eye phenotype ( J:83125 , J:139239 )

N • unlike Dstn^corn1 homozygotes corneal vascularization is not seen (J:83125)

N • unlike Dstn^corn1 homozygotes neutrophil and macrophage infiltration of the cornea is not seen (J:139239)

abnormal cornea epithelium morphology ( J:83125 )

• epithelial lesion characterized by focal epithelial thickening and enlarged surface

• epithelial cells with degenerating nuclei

• phenotype is milder than in Dstn^corn1 homozygotes

Genotype
MGI:3817224

ht2

• Allelic Composition: Dstn^corn1/Dstn^corn1-2J
• Genetic Background: involves: A/WySn * brachy stock * C57BL/6JSmn

vision/eye

vision/eye phenotype ( J:83125 )

N • unlike Dstn^corn1 homozygotes corneal vascularization is not seen

cornea epithelium hyperplasia ( J:83125 )

• epithelial proliferation