Analysis Tools|
Allele Symbol Allele Name Allele ID |
Dab1tm3.1Cpr targeted mutation 3.1, Jonathan A Cooper MGI:2388312 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit a normal cerebellum and preplate splitting
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• late born neurons migrate into the marginal zone unlike in wild-type mice
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• the neocortical marginal zone is thinner than in wild-type mice and crowded with small cells
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• mice exhibit a splitting of the stratum pyramidale in the CA1 region
• the ectopic pyramidal layer is closer to the hippocampal fissure, further from the alveus and becomes the main layer in the CA2 region
• however, the CA3 region and dentate gyrus develop normally
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• late born neurons migrate into the marginal zone unlike in wild-type mice
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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