Phenotypes associated with this allele

• Allele Symbol: Tpgs1^{Gt(ROSA22)Sor}
• Allele Name: gene trap ROSA22, Philippe Soriano
• Allele ID: MGI:2388468
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tpgs1^Gt(ROSA22)Sor/Tpgs1^Gt(ROSA22)Sor	involves: 129S/SvEv * C57BL/6	MGI:2451045

Genotype
MGI:2451045

hm1

• Allelic Composition: Tpgs1^{Gt(ROSA22)Sor}/Tpgs1^{Gt(ROSA22)Sor}
• Genetic Background: involves: 129S/SvEv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:79292 )

• reduced fat content in adult male mice relative to wild-type littermates; reduced body weight not due to hypophagia or increased metabolic rate

behavior/neurological

submission towards male mice ( J:79292 )

• normal testosterone levels were detected

reproductive system

teratozoospermia ( J:79292 )

♂

abnormal sperm axoneme morphology ( J:79292 )

♂ • various sperm axoneme abnormalities, ranging from absence of outer or central microtubules to complete disorganization

absent sperm axonemal central pair ( J:79292 )

♂ • absence of central microtubules is observe

absent sperm flagellum ( J:79292 )

♂ • spermatozoa in epididymis lacked flagella

abnormal spermiogenesis ( J:79292 )

♂

male infertility ( J:79292 )

♂

cellular

teratozoospermia ( J:79292 )

♂

abnormal sperm axoneme morphology ( J:79292 )

♂ • various sperm axoneme abnormalities, ranging from absence of outer or central microtubules to complete disorganization

absent sperm axonemal central pair ( J:79292 )

♂ • absence of central microtubules is observe

absent sperm flagellum ( J:79292 )

♂ • spermatozoa in epididymis lacked flagella