Phenotypes associated with this allele

• Allele Symbol: Tg(CD4-HIV)F21388Pjo
• Allele Name: transgene insertion F21388, Paul Jolicoeur
• Allele ID: MGI:2388573
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(CD4-HIV)F21388Pjo/0	involves: C3H * C57BL/6	MGI:2450555

Genotype
MGI:2450555

tg1

• Allelic Composition: Tg(CD4-HIV)F21388Pjo/0
• Genetic Background: involves: C3H * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:77799 , J:78756 )

• animals display severe AIDS-like disease (J:77799)

• animals developed AIDS-like disease (J:78756)

• onset of disease varied between 30 days and 16 months (J:78756)

behavior/neurological

weakness ( J:78756 )

decreased locomotor activity ( J:78756 )

cardiovascular system

enlarged heart ( J:77799 )

• observed predominantly or exclusively on the left side

dystrophic cardiac calcinosis ( J:77799 )

• small white spots observed on surface of heart

digestive/alimentary system

diarrhea ( J:78756 )

growth/size/body

enlarged heart ( J:77799 )

• observed predominantly or exclusively on the left side

cachexia ( J:78756 )

hematopoietic system

thymus atrophy ( J:78756 )

spleen atrophy ( J:78756 )

homeostasis/metabolism

edema ( J:78756 )

immune system

thymus atrophy ( J:78756 )

spleen atrophy ( J:78756 )

lymph node atrophy ( J:78756 )

tubular nephritis ( J:78756 )

• tubulo-interstitial nephritis

interstitial pneumonia ( J:78756 )

renal/urinary system

tubular nephritis ( J:78756 )

• tubulo-interstitial nephritis

respiratory system

interstitial pneumonia ( J:78756 )

endocrine/exocrine glands

thymus atrophy ( J:78756 )