Phenotypes associated with this allele

• Allele Symbol: Tg(CD4-HIV)F27011Pjo
• Allele Name: transgene insertion F27011, Paul Jolicoeur
• Allele ID: MGI:2388587
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(CD4-HIV)F27011Pjo/0	involves: C3H * C57BL/6	MGI:2451114

Genotype
MGI:2451114

tg1

• Allelic Composition: Tg(CD4-HIV)F27011Pjo/0
• Genetic Background: involves: C3H * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:78756 )

• animals developed AIDS-like disease

• 50% of animals died at approximately 10 months of age

behavior/neurological

weakness ( J:78756 )

decreased locomotor activity ( J:78756 )

digestive/alimentary system

diarrhea ( J:78756 )

growth/size/body

cachexia ( J:78756 )

hematopoietic system

thymus atrophy ( J:78756 )

spleen atrophy ( J:78756 )

homeostasis/metabolism

edema ( J:78756 )

immune system

thymus atrophy ( J:78756 )

spleen atrophy ( J:78756 )

lymph node atrophy ( J:78756 )

tubular nephritis ( J:78756 )

• tubulo-interstitial nephritis

interstitial pneumonia ( J:78756 )

renal/urinary system

tubular nephritis ( J:78756 )

• tubulo-interstitial nephritis

respiratory system

interstitial pneumonia ( J:78756 )

endocrine/exocrine glands

thymus atrophy ( J:78756 )