All Phenotypes Psme1/Psme2<tm1Tchi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Psme1/Psme2^tm1Tchi
targeted mutation 1, Tomoki Chiba
MGI:2388601

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Psme1/Psme2^tm1Tchi/Psme1/Psme2^tm1Tchi	involves: C57BL/6 * CBA	MGI:3624632

Allelic Composition	Psme1/Psme2^tm1Tchi/Psme1/Psme2^tm1Tchi
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Psme1/Psme2^tm1Tchi mutation (2 available); any Psme2 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

abnormal tumor susceptibility ( J:108550 )

• anti-tumor immunity against Lewis lung carcinoma cells induced by immunization with the DNA vaccine pUB-MUT1 is almost completely abolished in mutant mice compared to comtrol; null mice completely fail to acquire anti-tumor immunity as evaluated by growth inhibition or prevention of metastasis of tumor cells in vivo after immunization

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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