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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Lck-Map3k8)3456Ngc
transgene insertion 3456, Neal G Copeland
MGI:2388710
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Lck-Map3k8)3456Ngc/? involves: C3H/HeJ * C57BL/6J MGI:2389022


Genotype
MGI:2389022
tg1
Allelic
Composition
Tg(Lck-Map3k8)3456Ngc/?
Genetic
Background
involves: C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• mice developed metastatic lymphoblastic lymphomas with an 88% incidence by 3 months of age
• tumors were shown to be of T-cell origin derived from cells at different stages of T-cell development

endocrine/exocrine glands
• mice developed metastatic lymphoblastic lymphomas with an 88% incidence by 3 months of age
• tumors were shown to be of T-cell origin derived from cells at different stages of T-cell development

hematopoietic system
• mice developed metastatic lymphoblastic lymphomas with an 88% incidence by 3 months of age
• tumors were shown to be of T-cell origin derived from cells at different stages of T-cell development

immune system
• mice developed metastatic lymphoblastic lymphomas with an 88% incidence by 3 months of age
• tumors were shown to be of T-cell origin derived from cells at different stages of T-cell development





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory