All Phenotypes Cdh1<tm2.1Kem> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cdh1^tm2.1Kem
targeted mutation 2.1, Rolf Kemler
MGI:2389021

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Cdh1^tm1Kem/Cdh1^tm2.1Kem	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6	MGI:3830622

Allelic Composition	Cdh1^tm1Kem/Cdh1^tm2.1Kem
Genetic Background	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdh1^tm1Kem mutation (1 available); any Cdh1 mutation (173 available)
Cdh1^tm2.1Kem mutation (0 available); any Cdh1 mutation (173 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal cell adhesion ( J:77170 )

• when treated with a cre-expressing plasmid, embryonic stem cells from E3.5 mice exhibit reduced cell to cell adhesion compared to wild-type embryonic cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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