Phenotypes associated with this allele

• Allele Symbol: Bmd5^C3H/HeJ
• Allele Name: C3H/HeJ
• Allele ID: MGI:2389153
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bmd5^C3H/HeJ/Bmd5^C3H/HeJ	B6.C3-(D1Mit282-D1Mit406)	MGI:3719115
hm2	Bmd5^C3H/HeJ/Bmd5^C3H/HeJ	involves: C3H/HeJ * C57BL/6J	MGI:2679687
ht3	Bmd5^C3H/HeJ/Bmd5^C57BL/6J	involves: C3H/HeJ * C57BL/6J	MGI:2679688

Genotype
MGI:3719115

hm1

• Allelic Composition: Bmd5^C3H/HeJ/Bmd5^C3H/HeJ
• Genetic Background: B6.C3-(D1Mit282-D1Mit406)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal bone remodeling ( J:123678 )

• decreased responsiveness to mechanical loading in males

• increased responsiveness to mechanical loading in females

Genotype
MGI:2679687

hm2

• Allelic Composition: Bmd5^C3H/HeJ/Bmd5^C3H/HeJ
• Genetic Background: involves: C3H/HeJ * C57BL/6J

growth/size/body

increased body weight ( J:85226 , J:86886 )

skeleton

increased bone mineral density of vertebrae ( J:78754 , J:85226 )

• increased vertebral BMD (J:78754)

• increased vertebral BMD (J:85226)

increased bone mineral density of femur ( J:78754 , J:85226 )

• increased femoral BMD (J:78754)

• increased femoral BMD (J:85226)

decreased compact bone area ( J:86886 )

♂ • reduced cortical area in male animals

Genotype
MGI:2679688

ht3

• Allelic Composition: Bmd5^C3H/HeJ/Bmd5^C57BL/6J
• Genetic Background: involves: C3H/HeJ * C57BL/6J

skeleton

increased bone mineral density of vertebrae ( J:78754 )

• increased vertebral BMD

increased bone mineral density of femur ( J:78754 )

• increased femoral BMD