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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Msh2tm1Tts
targeted mutation 1, Teruhisa Tsuzuki
MGI:2389314
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Msh2tm1Tts/Msh2tm1Tts
Nudt1tm1Tts/Nudt1tm1Tts
involves: 129S/SvEv * C57BL/6J MGI:3784584


Genotype
MGI:3784584
cx1
Allelic
Composition
Msh2tm1Tts/Msh2tm1Tts
Nudt1tm1Tts/Nudt1tm1Tts
Genetic
Background
involves: 129S/SvEv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Msh2tm1Tts mutation (0 available); any Msh2 mutation (95 available)
Nudt1tm1Tts mutation (0 available); any Nudt1 mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• spleen cells show a significant increase in frameshift mutations at mononucleotide runs relative to wild-type when assayed with a reporter system





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory