immune system
• following sensitization with ovalbumin and exposure to ovalbumin, IgE levels are 4-fold lower than in similarly trated wild-type mice
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• following sensitization with ovalbumin and exposure to ovalbumin, mice exhibit a 64% reduction in cellular inflammatory infiltrate in bronchoalveolar lavage (specifically, 73% less eosinophils, 71% less neutrophils, 49% less macrophages, and 59% less lymphocytes) compared to in similarly treated wild-type mice
• however, cellular composition of the inflammatory infiltrate is normal
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hematopoietic system
• following sensitization with ovalbumin and exposure to ovalbumin, IgE levels are 4-fold lower than in similarly trated wild-type mice
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