Phenotypes associated with this allele

• Allele Symbol: Socs6^tm1Dlk
• Allele Name: targeted mutation 1, Danielle L Krebs
• Allele ID: MGI:2429394
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Socs6^tm1Dlk/Socs6^tm1Dlk	involves: C57BL/6	MGI:3029172

Genotype
MGI:3029172

hm1

• Allelic Composition: Socs6^tm1Dlk/Socs6^tm1Dlk
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body weight ( J:77039 )

• homozygous animals weigh 8-10% less than controls

hematopoietic system

hematopoietic system phenotype ( J:77039 )

N • no anomaly in the number of white blood cells or platelets was detected; no differences in hematocrit of femoral bone marrow cell counts

N • cell types in peritoneal cavity, spleen, and bone marrow were normal

N • number of hematopoietic progenitor cells in the bone marrow was normal

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:77039 )

N • no abnormalities were detected in blood glucose or plasma insulin levels, or in glucose and insulin tolerance

immune system

immune system phenotype ( J:77039 )

N • counts of T and B lymphocytes, macrophages, granulocytes and erythroid cells were normal