About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		M6prtm1Psa
targeted mutation 1, Paul Saftig
MGI:2429535
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		M6prtm1Psa/M6prtm1Psa involves: 129P2/OlaHsd * C57BL/6 MGI:3619606
hm2
 		M6prtm1Psa/M6prtm1Psa involves: 129P2/OlaHsd * C57BL/6J MGI:3581054


Genotype
MGI:3619606
hm1
Allelic
Composition		 M6prtm1Psa/M6prtm1Psa
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
M6prtm1Psa mutation (1 available); any M6pr mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal enzyme/coenzyme level ( J:106558 )
• beta-D-galactosidase, N-acetylglucosaminidase and alpha-D-mannosidase levels in spermatazoa show increases of 17, 63 and 51% respectively in homozygous mutants




Genotype
MGI:3581054
hm2
Allelic
Composition		 M6prtm1Psa/M6prtm1Psa
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
M6prtm1Psa mutation (1 available); any M6pr mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:16151 )
• fewer than expected homozygotes produced
• normal phenotype otherwise




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory