Phenotypes associated with this allele

• Allele Symbol: Dab2^tm1Xxx
• Allele Name: targeted mutation 1, Xiang-Xi Xu
• Allele ID: MGI:2429678
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dab2^tm1Xxx/Dab2^tm1Xxx	involves: 129S6/SvEvTac * C57BL/6	MGI:2451360

Genotype
MGI:2451360

hm1

• Allelic Composition: Dab2^tm1Xxx/Dab2^tm1Xxx
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:79862 )

• death occurs between E3.5 - E10.5

embryo

absent inner cell mass proliferation ( J:79862 )

• inner cell mass fails to proliferate and expand

abnormal gastrulation ( J:79862 )

abnormal egg cylinder morphology ( J:79862 )

• disorganization of embryonic cells at the egg cylinder stage

cellular

absent inner cell mass proliferation ( J:79862 )

• inner cell mass fails to proliferate and expand