Phenotypes associated with this allele

• Allele Symbol: Hag
• Allele Name: hague
• Allele ID: MGI:2429754
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hag/Hag	C3H/HeN-Hag	MGI:3697446
ht2	Hag/Hag^+	C3H/HeN-Hag	MGI:3697447
cx3	Hag/Hag^+ Krt71^Ca/Krt71^+	involves: C3H/HeN * C57BL/6ByJ	MGI:3697449

Genotype
MGI:3697446

hm1

• Allelic Composition: Hag/Hag
• Genetic Background: C3H/HeN-Hag

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

focal hair loss ( J:79964 )

• patchy depilated areas apparent by 10 days of age

abnormal hair shaft morphology ( J:79964 )

• broken shafts are commonly seen

abnormal zigzag hair morphology ( J:79964 )

• poorly developed

Genotype
MGI:3697447

ht2

• Allelic Composition: Hag/Hag⁺
• Genetic Background: C3H/HeN-Hag

integument

waved hair ( J:79964 )

• partial penetrance

• curly hair is more obvious in young mice (less than 2 months of age)

• after 5 generations of inbreeding of homozygous mice the semi-dominant phenotype was lost and all heterozygotes had a wild-type hair phenotype

abnormal hair shaft morphology ( J:79964 )

• curled

Genotype
MGI:3697449

cx3

• Allelic Composition: Hag/Hag⁺; Krt71^Ca/Krt71⁺
• Genetic Background: involves: C3H/HeN * C57BL/6ByJ

integument

focal hair loss ( J:79964 )

• some mice display hairy and bald patches while others display a uniform caracul phenotype

waved hair ( J:79964 )

• some mice display hairy and bald patches while others display a uniform caracul phenotype

• within the hairy patches the hair is also curly