Phenotypes associated with this allele

• Allele Symbol: Tbp^tm1Idvd
• Allele Name: targeted mutation 1, Irwin Davidson
• Allele ID: MGI:2429772
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tbp^tm1Idvd/Tbp^tm1Idvd	involves: C57BL/6	MGI:3720052

Genotype
MGI:3720052

hm1

• Allelic Composition: Tbp^tm1Idvd/Tbp^tm1Idvd
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality at implantation, complete penetrance ( J:79959 )

• under culture conditions blastocysts undergo growth arrest and apoptosis

• while embryos are recovered at E4.5 they exhibit severe growth arrest with only 30 to 40 cells

embryo

embryonic growth arrest ( J:79959 )

• embryonic growth arrest occurs prior to E3.5

• under culture conditions E3.5 embryos undergo growth arrest and apoptosis