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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ccnb2tm1Thnt
targeted mutation 1, Tim Hunt
MGI:2429974
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ccnb2tm1Thnt/Ccnb2tm1Thnt involves: 129P2/OlaHsd * C57BL/6 MGI:2660700


Genotype
MGI:2660700
hm1
Allelic
Composition		 Ccnb2tm1Thnt/Ccnb2tm1Thnt
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccnb2tm1Thnt mutation (0 available); any Ccnb2 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:47430 )
• homozygous mutants are underrepresented in F2 progeny

growth/size/body
decreased body weight ( J:47430 )

reproductive system

hematopoietic system
small thymus ( J:47430 )
• thymus is somewhat smaller
increased double-negative T cell number ( J:47430 )
• slightly higher proportion of CD4-CD8 double-negative cells

immune system
small thymus ( J:47430 )
• thymus is somewhat smaller
increased double-negative T cell number ( J:47430 )
• slightly higher proportion of CD4-CD8 double-negative cells

endocrine/exocrine glands
small thymus ( J:47430 )
• thymus is somewhat smaller




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory