Phenotypes associated with this allele

• Allele Symbol: Gata2⁺
• Allele Name: wild type
• Allele ID: MGI:2430573
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Gata2^tm1b(KOMP)Wtsi/Gata2^+	C57BL/6N-Gata2^tm1b(KOMP)Wtsi/Tcp	MGI:5757158
ht2	Gata2^tm1Mym/Gata2^+	involves: 129P2/OlaHsd * C57BL/6	MGI:3620765

Genotype
MGI:5757158

ht1

• Allelic Composition: Gata2^{tm1b(KOMP)Wtsi}/Gata2⁺
• Genetic Background: C57BL/6N-Gata2^{tm1b(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0586_1_F06

Data Sources

IMPC Data for Gata2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

♀

IMPC - TCP

abnormal embryo size ( J:211773 )

♀

IMPC - TCP

endocrine/exocrine glands

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

♀

IMPC - TCP

abnormal embryo size ( J:211773 )

♀

IMPC - TCP

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD

reproductive system

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

abnormal epididymis morphology ( J:211773 )

♂

IMPC - UCD

enlarged epididymis ( J:211773 )

♂

IMPC - UCD

absent epididymis ( J:211773 )

♂

IMPC - UCD

Genotype
MGI:3620765

ht2

• Allelic Composition: Gata2^tm1Mym/Gata2⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

hematopoietic system

abnormal definitive hematopoiesis ( J:84836 )

• at E9.5, slightly increased numbers of CD45+ cells are seen in the yolk sac and at E11.5 impaired production of CD45+ and CD34+ cells is seen in the aorta-gonads-mesonephros region suggesting depletion of the precursor cells