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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fyn+
wild type
MGI:2430704
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Fyntm1Yik/Fyn+ involves: C57BL/6 * CBA MGI:3693457
cx2
 		Fyntm1Sor/Fyn+
Tg(Camk2a-Fyn-531)1Nko/0 		involves: 129S7/SvEvBrd * C57BL/6 * CBA MGI:2652121


Genotype
MGI:3693457
ht1
Allelic
Composition		 Fyntm1Yik/Fyn+
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fyntm1Yik mutation (1 available); any Fyn mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
prolonged circadian behavior period ( J:63170 )
• under constant dark condition, exhibit longer circadian periods in wheel-running activity than wild-type




Genotype
MGI:2652121
cx2
Allelic
Composition		 Fyntm1Sor/Fyn+
Tg(Camk2a-Fyn-531)1Nko/0
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fyntm1Sor mutation (3 available); any Fyn mutation (37 available)
Tg(Camk2a-Fyn-531)1Nko mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:59490 )
• sudden death after weaning; survival rate shows correlation with level of transgene expression

behavior/neurological
abnormal motor capabilities/coordination/movement ( J:59490 )
• lines expressing high levels of the transgene show spontaneous running and bouncing fits
tonic seizures ( J:59490 )
• tonic convulsion

nervous system
tonic seizures ( J:59490 )
• tonic convulsion




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory