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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hoxa10+
wild type
MGI:2430903
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Hoxa10tm1Ipc/Hoxa10+ either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6) MGI:3819800
cx2
 		Hoxa10tm1Mrc/Hoxa10+
Hoxc10tm1Mrc/Hoxc10tm1Mrc
Hoxd10tm1Mrc/Hoxd10tm1Mrc 		involves: 129S1/Sv * 129X1/SvJ MGI:3844344


Genotype
MGI:3819800
ht1
Allelic
Composition		 Hoxa10tm1Ipc/Hoxa10+
Genetic
Background		 either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa10tm1Ipc mutation (0 available); any Hoxa10 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal axial skeleton morphology ( J:28593 )
• heterozygotes displayed similar but milder axial skeleton homeosis and rib alterations than those seen in homozygotes (not shown)




Genotype
MGI:3844344
cx2
Allelic
Composition		 Hoxa10tm1Mrc/Hoxa10+
Hoxc10tm1Mrc/Hoxc10tm1Mrc
Hoxd10tm1Mrc/Hoxd10tm1Mrc
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa10tm1Mrc mutation (0 available); any Hoxa10 mutation (19 available)
Hoxc10tm1Mrc mutation (0 available); any Hoxc10 mutation (17 available)
Hoxd10tm1Mrc mutation (0 available); any Hoxd10 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
increased rib number ( J:84456 )
• mice possess a fourteenth rib

limbs/digits/tail
abnormal forelimb stylopod morphology ( J:84456 )
• mice exhibit an intermediate stylopod morphology between wild-type mice and triple homozygotes
abnormal hindlimb stylopod morphology ( J:84456 )
• mice exhibit an intermediate stylopod morphology between wild-type mice and triple homozygotes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory