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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hspa1a+
wild type
MGI:2430949
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Hspa1atm1Msk/Hspa1a+ involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 MGI:3719791


Genotype
MGI:3719791
ht1
Allelic
Composition		 Hspa1atm1Msk/Hspa1a+
Genetic
Background		 involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hspa1atm1Msk mutation (0 available); any Hspa1a mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell physiology ( J:72943 )
• in an in vitro assay, macrophages are more sensitive to thermal stress than wild-type macrophages but not as sensitive as Hspa1atm1Msk homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory