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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Prkcg+
wild type
MGI:2431712
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Prkcgem1Jpka/Prkcg+ FVB/N-Prkcgem1Jpka MGI:6865691


Genotype
MGI:6865691
ht1
Allelic
Composition
Prkcgem1Jpka/Prkcg+
Genetic
Background
FVB/N-Prkcgem1Jpka
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkcgem1Jpka mutation (0 available); any Prkcg mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice show marked ataxia at 3 and 6 months of age on the balance beam test
• footprint gait analysis of 9-month-old mice shows an ataxic gait with increased step width

nervous system
• dendritic expansion of Purkinje cells in organotypic slice culture is severely impaired and cells develop only short thickened dendrites

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
spinocerebellar ataxia type 14 DOID:0050964 OMIM:605361
J:305637





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory