All Phenotypes Tyr<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tyr⁺
wild type
MGI:2432472

Summary

8 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Tyr^c-26DVT/Tyr⁺	involves: 101/Rl * C3H/Rl * T-stock	MGI:5293748
ht2	Tyr^c-ch83R/Tyr⁺	involves: 101/Rl * C3H/Rl * T-stock	MGI:5294374
ht3	Tyr^c-25H/Tyr⁺	involves: AKR * STOCK Tyr^c-25H/Tyr^c-ch	MGI:3691584
ht4	Tyr^c-25H/Tyr⁺	involves: SM/J * STOCK Tyr^c-h/Tyr^c-25H	MGI:3691849
cx5	Tyr^c/Del(7)Tyr^c-3H	involves: 101/H * C3H/HeH	MGI:4431254
cx6	Tyr^c-ch/Del(7)Tyr^c-3H	involves: 101/H * C3H/HeH	MGI:4431256
cx7	Tyr^c-ch/Del(7)Tyr^c-6H	involves: 101/H * C3H/HeH	MGI:4843178
cx8	Tenm4^l7Rn3-4R/Tyr^c-26DVT	involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock	MGI:3789295

Allelic Composition	Tyr^c-26DVT/Tyr⁺
Genetic Background	involves: 101/Rl * C3H/Rl * T-stock

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c-26DVT mutation (2 available); any Tyr mutation (379 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:100221 )

Allelic Composition	Tyr^c-ch83R/Tyr⁺
Genetic Background	involves: 101/Rl * C3H/Rl * T-stock

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c-ch83R mutation (0 available); any Tyr mutation (379 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:100221 )

• appears wild-type

Allelic Composition	Tyr^c-25H/Tyr⁺
Genetic Background	involves: AKR * STOCK Tyr^c-25H/Tyr^c-ch

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c-25H mutation (0 available); any Tyr mutation (379 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal chromosome morphology ( J:5520 )

• this allele includes a deletion, detected in banded mitotic chromosomes, comprising 1-6cM, representing about 7.6% of Chr 7

induced chromosome breakage ( J:5520 )

Allelic Composition	Tyr^c-25H/Tyr⁺
Genetic Background	involves: SM/J * STOCK Tyr^c-h/Tyr^c-25H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c-25H mutation (0 available); any Tyr mutation (379 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

chromosome breakage ( J:5437 )

induced chromosome breakage ( J:5437 )

• an induced, associated deletion involves, minimally, the MOD2 structural locus

Allelic Composition	Tyr^c/Del(7)Tyr^c-3H
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7)Tyr^c-3H mutation (0 available); any Del(7)Tyr^c-3H mutation (0 available)
Tyr^c mutation (80 available); any Tyr mutation (379 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

absent coat pigmentation ( J:5063 )

• this mouse is albino

integument

absent coat pigmentation ( J:5063 )

• this mouse is albino

Allelic Composition	Tyr^c-ch/Del(7)Tyr^c-3H
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7)Tyr^c-3H mutation (0 available); any Del(7)Tyr^c-3H mutation (0 available)
Tyr^c-ch mutation (79 available); any Tyr mutation (379 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:5063 )

diluted coat color ( J:5063 )

• the coat color is intermediate between that expected for an albino mouse and a mouse homozygous for chinchilla

integument

abnormal coat/hair pigmentation ( J:5063 )

diluted coat color ( J:5063 )

• the coat color is intermediate between that expected for an albino mouse and a mouse homozygous for chinchilla

Allelic Composition	Tyr^c-ch/Del(7)Tyr^c-6H
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7)Tyr^c-6H mutation (1 available); any Del(7)Tyr^c-6H mutation (0 available)
Tyr^c-ch mutation (79 available); any Tyr mutation (379 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:5741 )

diluted coat color ( J:5741 )

• these mice are noticeably lighter in color than mice that are homozygous chinchilla

integument

abnormal coat/hair pigmentation ( J:5741 )

diluted coat color ( J:5741 )

• these mice are noticeably lighter in color than mice that are homozygous chinchilla

Allelic Composition	Tenm4^l7Rn3-4R/Tyr^c-26DVT
Genetic Background	involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tenm4^l7Rn3-4R mutation (0 available); any Tenm4 mutation (302 available)
Tyr^c-26DVT mutation (2 available); any Tyr mutation (379 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:96673 )

N	• when the Odz4^l7Rn3-4R allele is inherited from the father, animals survive to adulthood

prenatal lethality, complete penetrance ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, animals die as embryos between E8.5 and E17.5

cardiovascular system

abnormal vasculogenesis ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, defects in vascularization are seen

embryo

embryonic growth retardation ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, developmental delay is seen

abnormal limb bud morphology ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, abnormalities in limb bud elongation are seen

kinked neural tube ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, kinky neural tubes are observed

growth/size/body

embryonic growth retardation ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, developmental delay is seen

decreased body size ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the father, 30% of animals appear runted and scruffy at weaning

limbs/digits/tail

abnormal limb bud morphology ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, abnormalities in limb bud elongation are seen

nervous system

kinked neural tube ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, kinky neural tubes are observed

skeleton

thoracic vertebral fusion ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the father, 27% of mutant animals display lumbar and/or thoracic vertebral fusions

abnormal cervical axis morphology ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the father, an aberrant spinous process is observed in 18% of mutant animals

lumbar vertebral fusion ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the father, 27% of mutant animals display lumbar and/or thoracic vertebral fusions

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