Analysis Tools
embryo
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IMPC - BCM
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growth/size/body
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IMPC - BCM
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Allele Symbol Allele Name Allele ID |
Prdm1+ wild type MGI:2432646 |
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| Summary |
8 genotypes
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Data Sources
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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IMPC - BCM
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IMPC - BCM
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at E7.5 primordial germ cell numbers are reduced to about 17.5 cells compared to about 25 cells in wild-type mice; however the cells that are present appear to migrate properly
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• at E7.5 primordial germ cell numbers are reduced to about 17.5 cells compared to about 25 cells in wild-type mice; however the cells that are present appear to migrate properly
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at E7.75 and E9.0-9.5, the number of primordial germ cells is reduced and extrapolation indicates that the founding population of primordial germ cells is reduced by 78% compared to wild-type mice, 9 cells versus 40 cells in wild-type
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• at E7.75 and E9.0-9.5, the number of primordial germ cells is reduced and extrapolation indicates that the founding population of primordial germ cells is reduced by 78% compared to wild-type mice, 9 cells versus 40 cells in wild-type
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at E7.75 and E9.0-9.5, the number of primordial germ cells is reduced and extrapolation indicates that the founding population of primordial germ cells is reduced by 78% compared to wild-type mice, 9 cells versus 40 cells in wild-type
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• at E7.75 and E9.0-9.5, the number of primordial germ cells is reduced and extrapolation indicates that the founding population of primordial germ cells is reduced by 78% compared to wild-type mice, 9 cells versus 40 cells in wild-type
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• at E7.75 and E9.0-9.5, the number of primordial germ cells is reduced and extrapolation indicates that the founding population of primordial germ cells is reduced by 78% compared to wild-type mice, 9 cells versus 40 cells in wild-type
|
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• at E7.75 and E9.0-9.5, the number of primordial germ cells is reduced and extrapolation indicates that the founding population of primordial germ cells is reduced by 78% compared to wild-type mice, 9 cells versus 40 cells in wild-type
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice show no significant differences in the frequency of bone marrow plasma cells, splenic plasma cells and splenic plasmablasts, or in the serum concentrations of IgM, IgG1, IgG2b, IgG2c, IgG3 or IgA relative to wild-type controls
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice show no significant differences in the frequency of bone marrow plasma cells, splenic plasma cells and splenic plasmablasts, or in the serum concentrations of IgM, IgG1, IgG2b, IgG2c, IgG3 or IgA relative to wild-type controls
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice show no significant differences in the frequency of bone marrow plasma cells, splenic plasma cells and splenic plasmablasts, or in the serum concentrations of IgM, IgG1, IgG2b, IgG2c, IgG3 or IgA relative to wild-type controls
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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