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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mki67+
wild type
MGI:2433638
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Mki67em1Dfis/Mki67+ involves: C57BL/6J MGI:6715306


Genotype
MGI:6715306
ht1
Allelic
Composition		 Mki67em1Dfis/Mki67+
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mki67em1Dfis mutation (0 available); any Mki67 mutation (147 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased tumor growth/size ( J:304800 )
• 16 weeks after induction of colon tumors by azoxymethane/dextran sodium sulfate (AOM-DSS) treatment, heterozygotes show a significant increase in total lesion area (mm2) but no difference in the total number of lesions/mouse relative to similarly treated wild-type controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory