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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bco2+
wild type
MGI:2436526
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Bco2tm1Dnp/Bco2+ involves: 129S6/SvEvTac * C57BL/6 MGI:4947682


Genotype
MGI:4947682
ht1
Allelic
Composition		 Bco2tm1Dnp/Bco2+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bco2tm1Dnp mutation (0 available); any Bco2 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
liver/biliary system
increased liver triglyceride level ( J:170742 )
• in mice fed a diet supplemented with zeaxanthin
macrovesicular hepatic steatosis ( J:170742 )
• mice fed a diet supplemented with zeaxanthin exhibit liver steatosis with large lipid droplets unlike wild-type mice

homeostasis/metabolism
increased liver triglyceride level ( J:170742 )
• in mice fed a diet supplemented with zeaxanthin




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory