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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Apcs+
wild type
MGI:2436899
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Apcstm1Mpe/Apcs+ B6.Cg-Apcstm1Mpe MGI:3775476


Genotype
MGI:3775476
ht1
Allelic
Composition		 Apcstm1Mpe/Apcs+
Genetic
Background		 B6.Cg-Apcstm1Mpe
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apcstm1Mpe mutation (0 available); any Apcs mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal spleen red pulp morphology ( J:90502 )
• mice exhibit red pulp lymphocytosis
abnormal spleen white pulp morphology ( J:90502 )
• mice exhibit coalescence of white pulp
increased autoantibody level ( J:90502 )
• intermediate increase with females more affected
glomerulonephritis ( J:90502 )
• mice, particularly females, exhibit intermediate frequency of proliferative, immune complex glomerulonephritis compared to wild-type mice

renal/urinary system
glomerulonephritis ( J:90502 )
• mice, particularly females, exhibit intermediate frequency of proliferative, immune complex glomerulonephritis compared to wild-type mice

hematopoietic system
abnormal spleen red pulp morphology ( J:90502 )
• mice exhibit red pulp lymphocytosis
abnormal spleen white pulp morphology ( J:90502 )
• mice exhibit coalescence of white pulp




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory