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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Trex1+
wild type
MGI:2437255
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Trex1tm1.1Fwpe/Trex1+ involves: 129S1/SvImJ * 129S4/SvJae * 129S6/SvEvTac MGI:5781126


Genotype
MGI:5781126
ht1
Allelic
Composition		 Trex1tm1.1Fwpe/Trex1+
Genetic
Background		 involves: 129S1/SvImJ * 129S4/SvJae * 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trex1tm1.1Fwpe mutation (0 available); any Trex1 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased CD4-positive, alpha-beta T cell number ( J:220965 )
• increased number of CD4+ T cells in spleen
• however, heterozygous mice show normal survival and rather minimal inflammatory differences relative to wild-type controls

hematopoietic system
increased CD4-positive, alpha-beta T cell number ( J:220965 )
• increased number of CD4+ T cells in spleen
• however, heterozygous mice show normal survival and rather minimal inflammatory differences relative to wild-type controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory