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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tlk2+
wild type
MGI:2438125
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Tlk2em1(IMPC)Bay/Tlk2+ C57BL/6N-Tlk2em1(IMPC)Bay/BayMmucd MGI:7317080
cx2
 		Tlk1Gt(E067A02)Wrst/Tlk1Gt(E067A02)Wrst
Tlk2tm1Strc/Tlk2+ 		involves: 129P2/OlaHsd * C57BL/6J MGI:6274370


Genotype
MGI:7317080
ht1
Allelic
Composition		 Tlk2em1(IMPC)Bay/Tlk2+
Genetic
Background		 C57BL/6N-Tlk2em1(IMPC)Bay/BayMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tlk2em1(IMPC)Bay mutation (1 available); any Tlk2 mutation (71 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton




Genotype
MGI:6274370
cx2
Allelic
Composition		 Tlk1Gt(E067A02)Wrst/Tlk1Gt(E067A02)Wrst
Tlk2tm1Strc/Tlk2+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tlk1Gt(E067A02)Wrst mutation (0 available); any Tlk1 mutation (209 available)
Tlk2tm1Strc mutation (0 available); any Tlk2 mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:268910 )
• all moribund by 1 month of age due to lack of mobility and tremors

growth/size/body
decreased body size ( J:268910 )
• severely runted at p2 - p25

behavior/neurological
decreased locomotor activity ( J:268910 )
• lack of mobility




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory