All Phenotypes Igfbp7<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Igfbp7⁺
wild type
MGI:2438500

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Igfbp7^tm1.1Dds/Igfbp7⁺	involves: CD-1	MGI:5661468

Allelic Composition	Igfbp7^tm1.1Dds/Igfbp7⁺
Genetic Background	involves: CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igfbp7^tm1.1Dds mutation (0 available); any Igfbp7 mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

abnormal branching of the mammary ductal tree ( J:212964 )

• at 11 weeks of age, virgin heterozygotes display a significant reduction in mammary ductal tips, although to a lesser extent than that observed in homozygotes

abnormal mammary duct terminal end bud morphology ( J:212964 )

• at 3 weeks, virgin heterogotes display a significantly decreased number of terminal end buds (TEBs), comparable to that observed in homozygotes

integument

abnormal branching of the mammary ductal tree ( J:212964 )

• at 11 weeks of age, virgin heterozygotes display a significant reduction in mammary ductal tips, although to a lesser extent than that observed in homozygotes

abnormal mammary duct terminal end bud morphology ( J:212964 )

• at 3 weeks, virgin heterogotes display a significantly decreased number of terminal end buds (TEBs), comparable to that observed in homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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