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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nxph1tm1Sud
targeted mutation 1, Thomas C Sudhof
MGI:2445315
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nxph1tm1Sud/Nxph1tm1Sud involves: 129S6/SvEvTac MGI:3706516
cx2
 		Nxph1tm1Sud/Nxph1tm1Sud
Nxph3tm1.1Mami/Nxph3tm1.1Mami 		involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * FVB/N MGI:3706517


Genotype
MGI:3706516
hm1
Allelic
Composition		 Nxph1tm1Sud/Nxph1tm1Sud
Genetic
Background		 involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxph1tm1Sud mutation (0 available); any Nxph1 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal spermatogenesis ( J:51648 )
• appears to be an artifact of homologous recombination
male infertility ( J:51648 )
• appears to be an artifact of homologous recombination

mortality/aging
mortality/aging ( J:119861 )
N
• no change in viability compared to wild-type mice

growth/size/body
growth/size/body region phenotype ( J:119861 )
N
• body weight is not different from wild-type




Genotype
MGI:3706517
cx2
Allelic
Composition		 Nxph1tm1Sud/Nxph1tm1Sud
Nxph3tm1.1Mami/Nxph3tm1.1Mami
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxph1tm1Sud mutation (0 available); any Nxph1 mutation (15 available)
Nxph3tm1.1Mami mutation (0 available); any Nxph3 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:119861 )
N
• no change in viability compared to wild-type mice

growth/size/body
growth/size/body region phenotype ( J:119861 )
N
• body weight is not different from wild-type




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory