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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		St3gal2tm1Jxm
targeted mutation 1, Jamey Marth
MGI:2445397
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		St3gal2tm1Jxm/St3gal2tm1Jxm involves: C57BL/6 MGI:3036871
hm2
 		St3gal2tm1Jxm/St3gal2tm1Jxm Not Specified MGI:5615692


Genotype
MGI:3036871
hm1
Allelic
Composition		 St3gal2tm1Jxm/St3gal2tm1Jxm
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
St3gal2tm1Jxm mutation (0 available); any St3gal2 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:80119 )
N
• erythroid profiles within normal range
• numbers of lymphocytes in circulation were normal




Genotype
MGI:5615692
hm2
Allelic
Composition		 St3gal2tm1Jxm/St3gal2tm1Jxm
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
St3gal2tm1Jxm mutation (0 available); any St3gal2 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased T cell number ( J:217719 )
• increased frequency in the spleen
increased spleen germinal center size ( J:217719 )
• prominent in 10 of 15 mice compared with 6 of 16 wild-type mice

homeostasis/metabolism
increased bleeding time ( J:217719 )
• slight with a slight decrease in antiplasmin concentrations

hematopoietic system
increased T cell number ( J:217719 )
• increased frequency in the spleen
increased spleen germinal center size ( J:217719 )
• prominent in 10 of 15 mice compared with 6 of 16 wild-type mice

cellular




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory