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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Tek-cre)5326Sato
transgene insertion 5326, Thomas N Sato
MGI:2445474
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gja1tm1Kdr/Gja1tm1Kwi
Tg(Tek-cre)5326Sato/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J MGI:3621038
cn2
 		Flvcr2tm1.1Tda/Flvcr2tm1.1Tda
Tg(Tek-cre)5326Sato/0 		involves: C57BL/6J MGI:6415686


Genotype
MGI:3621038
cn1
Allelic
Composition		 Gja1tm1Kdr/Gja1tm1Kwi
Tg(Tek-cre)5326Sato/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja1tm1Kdr mutation (1 available); any Gja1 mutation (60 available)
Gja1tm1Kwi mutation (1 available); any Gja1 mutation (60 available)
Tg(Tek-cre)5326Sato mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:78662 )
• mutants lacking Gja1 in endothelium are viable, fertile, and show no abnormalities in the heart, brain, retina, pancreas, liver, kidney, spleen, testis, or blood pressure




Genotype
MGI:6415686
cn2
Allelic
Composition		 Flvcr2tm1.1Tda/Flvcr2tm1.1Tda
Tg(Tek-cre)5326Sato/0
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flvcr2tm1.1Tda mutation (0 available); any Flvcr2 mutation (25 available)
Tg(Tek-cre)5326Sato mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:287134 )
• as in null mice, no mice are present at weaning

cardiovascular system
abnormal vascular development ( J:287134 )
• as in null mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory