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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tir4C57BL/6JOlaHsd
C57BL/6JOlaHsd
MGI:2445530
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tir4C57BL/6JOlaHsd/Tir4C57BL/6JOlaHsd A.B6-(D17Mit29-D17Mit11) MGI:3794642
hm2
 		Tir4C57BL/6JOlaHsd/Tir4C57BL/6JOlaHsd A.B6-Tir1 MGI:3578869
hm3
 		Tir4C57BL/6JOlaHsd/Tir4C57BL/6JOlaHsd involves: A/JOlaHsd * C57BL/6JOlaHsd MGI:3042242
hm4
 		Tir4C57BL/6JOlaHsd/Tir4C57BL/6JOlaHsd involves: BALB/cOlaHsd * C57BL/6JOlaHsd MGI:3042243
ot5
 		Tir4C57BL/6JOlaHsd/? involves: BALB/cOlaHsd * C57BL/6JOlaHsd MGI:3042244


Genotype
MGI:3794642
hm1
Allelic
Composition		 Tir4C57BL/6JOlaHsd/Tir4C57BL/6JOlaHsd
Genetic
Background		 A.B6-(D17Mit29-D17Mit11)
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to parasitic infection ( J:135428 )
• increased survival time (23.3 days longer) after infection with T. congolense
• This locus accounts for 24.3% of the phenotypic variance




Genotype
MGI:3578869
hm2
Allelic
Composition		 Tir4C57BL/6JOlaHsd/Tir4C57BL/6JOlaHsd
Genetic
Background		 A.B6-Tir1
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to parasitic infection ( J:97672 )
• mean survival time of 57.9 days following infection with Trypanosome congolense




Genotype
MGI:3042242
hm3
Allelic
Composition		 Tir4C57BL/6JOlaHsd/Tir4C57BL/6JOlaHsd
Genetic
Background		 involves: A/JOlaHsd * C57BL/6JOlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to parasitic infection ( J:40771 )
• resistance to infection by Trypanosome congolense




Genotype
MGI:3042243
hm4
Allelic
Composition		 Tir4C57BL/6JOlaHsd/Tir4C57BL/6JOlaHsd
Genetic
Background		 involves: BALB/cOlaHsd * C57BL/6JOlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to parasitic infection ( J:40771 )
• resistance to infection by Trypanosome congolense




Genotype
MGI:3042244
ot5
Allelic
Composition		 Tir4C57BL/6JOlaHsd/?
Genetic
Background		 involves: BALB/cOlaHsd * C57BL/6JOlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to parasitic infection ( J:40771 )
• resistance to infection by Trypanosome congolense




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory