About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mybl2tm1Sis
targeted mutation 1, Shunsuke Ishii
MGI:2445746
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mybl2tm1Sis/Mybl2tm1Sis involves: C57BL/6 * CBA MGI:3528088


Genotype
MGI:3528088
hm1
Allelic
Composition		 Mybl2tm1Sis/Mybl2tm1Sis
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mybl2tm1Sis mutation (1 available); any Mybl2 mutation (114 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:57999 )
• shortly after uterine implantation, between E3.5 and E6.5

embryo
abnormal inner cell mass morphology ( J:57999 )
• little or no development of the inner cell mass in cultured embryos
• however, the trophectoderm develops normally




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory