Analysis Tools|
Allele Symbol Allele Name Allele ID |
Igf2rtm2Wag targeted mutation 2, Erwin F Wagner MGI:2445841 |
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| Summary |
4 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• when the allele is inherited paternally, mice exhibit a 20% decrease in weight compared to wild-type mice beginning at E17.5 and continuing throughout adulthood
• however, when this allele is inherited maternally mice have normal weights
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• when the allele is inherited paternally, mice are viable
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| N |
• when the allele is inherited paternally, mice are fertile
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| N |
• when the allele is inherited paternally, body weights are normal
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• rescue of preweaning lethality observed when Igf2rtm1.1(IGF2R)Arte is inherited maternally
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• when is Igf2rtm2Wag inherited paternally and Thp is maternally, some mice survive birth and reach maturity despite some prenatal lethality
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• when the allele is inherited paternally, fewer than expected mice are born
• however, unlike when only Thp is inherited maternally, some mice are recovered at birth
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• when is Igf2rtm2Wag inherited paternally and Thp is maternally, mice have a bent tail compared to wild-type mice
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| N |
• when the allele is inherited paternally, mice are fertile
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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