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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rdh5tm1Wsb
targeted mutation 1, William S Blaner
MGI:2446073
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rdh5tm1Wsb/Rdh5tm1Wsb involves: 129 * C57BL/6J MGI:3723300


Genotype
MGI:3723300
hm1
Allelic
Composition		 Rdh5tm1Wsb/Rdh5tm1Wsb
Genetic
Background		 involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rdh5tm1Wsb mutation (0 available); any Rdh5 mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal eye electrophysiology ( J:75693 )
• regeneration of rhodopsin after prolonged photobleaching is much slower than in wild-type accompanied by an elevation in total cis-retinol levels
delayed dark adaptation ( J:75693 )
• recovery from light adaptation is altered; the a-wave amplitude recovers more slowly
• total 11/13-cis-retinol levels are elevated in dark-adapted mutants




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/24/2024
MGI 6.24 		The Jackson Laboratory