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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Galr1tm1Tpi
targeted mutation 1, Tiina Pauline Iismaa
MGI:2446477
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Galr1tm1Tpi/Galr1tm1Tpi B6.129S1-Galr1tm1Tpi MGI:5613185
hm2
 		Galr1tm1Tpi/Galr1tm1Tpi involves: 129S1/Sv MGI:3051423


Genotype
MGI:5613185
hm1
Allelic
Composition		 Galr1tm1Tpi/Galr1tm1Tpi
Genetic
Background		 B6.129S1-Galr1tm1Tpi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Galr1tm1Tpi mutation (1 available); any Galr1 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
impaired conditioned place preference behavior ( J:214920 )
• mice exhibit no significant morphine conditioned place preference unlike wild-type mice

nervous system
abnormal excitatory postsynaptic potential ( J:214920 )
• mice exhibit no change in excitatory postsynaptic potential amplitude after application of galanin unlike in wild-type mice




Genotype
MGI:3051423
hm2
Allelic
Composition		 Galr1tm1Tpi/Galr1tm1Tpi
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Galr1tm1Tpi mutation (1 available); any Galr1 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:91683 )
N
• mutants respond normally with a decrease in food intake to intracerebroventricular injections of Galp




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory