About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Reg1tm1Okam
targeted mutation 1, Hiroshi Okamoto
MGI:2446480
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Reg1tm1Okam/Reg1tm1Okam involves: C57BL/6 * CBA * ICR MGI:3046063


Genotype
MGI:3046063
hm1
Allelic
Composition
Reg1tm1Okam/Reg1tm1Okam
Genetic
Background
involves: C57BL/6 * CBA * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Reg1tm1Okam mutation (0 available); any Reg1 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
N
• pancreatic islets were of normal size
• [3-H] thymidine uptake in isolated pancreatic islets was reduced in mutant mice
• goldthioglucose-induced islet hyperplasia was attenuated in mutant mice

homeostasis/metabolism
N
• urine and blood glucose levels were normal

reproductive system
N
• mice had normal fertility and litter sizes





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory