Phenotypes associated with this allele

• Allele Symbol: Tenm4⁺
• Allele Name: wild type
• Allele ID: MGI:2447064
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tenm4^l7Rn3-4R/Tyr^c-26DVT	involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock	MGI:3789295

Genotype
MGI:3789295

cx1

• Allelic Composition: Tenm4^l7Rn3-4R/Tyr^c-26DVT
• Genetic Background: involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:96673 )

N • when the Odz4^l7Rn3-4R allele is inherited from the father, animals survive to adulthood

prenatal lethality, complete penetrance ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, animals die as embryos between E8.5 and E17.5

cardiovascular system

abnormal vasculogenesis ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, defects in vascularization are seen

embryo

embryonic growth retardation ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, developmental delay is seen

abnormal limb bud morphology ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, abnormalities in limb bud elongation are seen

kinked neural tube ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, kinky neural tubes are observed

growth/size/body

embryonic growth retardation ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, developmental delay is seen

decreased body size ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the father, 30% of animals appear runted and scruffy at weaning

limbs/digits/tail

abnormal limb bud morphology ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, abnormalities in limb bud elongation are seen

nervous system

kinked neural tube ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the mother, kinky neural tubes are observed

skeleton

thoracic vertebral fusion ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the father, 27% of mutant animals display lumbar and/or thoracic vertebral fusions

abnormal cervical axis morphology ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the father, an aberrant spinous process is observed in 18% of mutant animals

lumbar vertebral fusion ( J:96673 )

• when the Odz4^l7Rn3-4R allele is inherited from the father, 27% of mutant animals display lumbar and/or thoracic vertebral fusions