Phenotypes associated with this allele

• Allele Symbol: Guca2a^tm1.1Mcoh
• Allele Name: targeted mutation 1.1, Mitchell B Cohen
• Allele ID: MGI:2447173
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Guca2a^tm1.1Mcoh/Guca2a^tm1.1Mcoh	involves: 129P2/OlaHsd * BALB/c	MGI:3820078

Genotype
MGI:3820078

hm1

• Allelic Composition: Guca2a^tm1.1Mcoh/Guca2a^tm1.1Mcoh
• Genetic Background: involves: 129P2/OlaHsd * BALB/c

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

abnormal enterocyte proliferation ( J:80545 )

• increased proliferation rate of epithelial cells in the colon

• increased migration rate of epithelial cells in crypts of the colon

abnormal large intestine crypts of Lieberkuhn morphology ( J:80545 )

• depth of crypt glands is increased about 10%

• number of epithelial cells per crypt increased about 10%

endocrine/exocrine glands

abnormal large intestine crypts of Lieberkuhn morphology ( J:80545 )

• depth of crypt glands is increased about 10%

• number of epithelial cells per crypt increased about 10%

cellular

abnormal enterocyte proliferation ( J:80545 )

• increased proliferation rate of epithelial cells in the colon

• increased migration rate of epithelial cells in crypts of the colon