Phenotypes associated with this allele

• Allele Symbol: Cbfb^tm2Ppl
• Allele Name: targeted mutation 2, Pu P Liu
• Allele ID: MGI:2447293
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cbfb^tm2Ppl/Cbfb^tm2Ppl	involves: 129S6/SvEvTac	MGI:2652660

Genotype
MGI:2652660

hm1

• Allelic Composition: Cbfb^tm2Ppl/Cbfb^tm2Ppl
• Genetic Background: involves: 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:79376 , J:80669 )

• animals die shortly after birth (J:79376)

• animals die shortly after birth (J:80669)

limbs/digits/tail

short tibia ( J:80669 )

skeleton

short tibia ( J:80669 )

abnormal chondrocyte morphology ( J:80669 )

• proliferating and hypertrophic chondrocytes appear less disorganized

delayed bone ossification ( J:80669 )